منابع مشابه
Effect of disodium cromoglycate on exercise-induced asthma.
In eight patients with exercise-induced asthma, disodium cromoglycate was found to produce a definite inhibition of the post-exercise fall in forced expiratory volume in one second. This effect may be part of the cause for the subjective improvement experienced with this drug.
متن کاملComparison of actions of disodium cromoglycate and ketotifen on exercise-induced bronchoconstriction in childhood asthma.
Ketotifen (Zaditen), a benzocycloheptathiophene derivative, is a new oral agent for treating asthma, with action similar in some respects to that of sodium cromoglycate. It is well established that sodium cromoglycate protects against antigen challenge by inhibiting the release of chemical mediators from mast cells. It also inhibits exerciseinduced bronchoconstriction and has bronchodilator pro...
متن کاملDisodium cromoglycate in the prevention of induced asthma.
In 13 patients with allergic asthma disodium cromoglycate protected fully only two from an allergen-induced asthmatic attack.Inhalation of disodium cromoglycate did not improve lung function in five patients with long-standing chronic asthma.Previous clinical trials do not show convincing evidence that this drug improves bronchial asthma in a high percentage of cases, but it seems to help a sma...
متن کاملChange in osmolarity of disodium cromoglycate solution and protection against exercise-induced bronchospasm in children with asthma.
It has been suggested that osmolarity and/or nebulizer output may affect the protective effects of disodium cromoglycate (DSCG) in asthma. The aim of this study was to evaluate the influence of osmolarity of the DSCG solution on exercise-induced bronchospasm (EIB) in children with bronchial asthma. A jet nebulizer was used for DSCG inhalation in Study 1 and an ultrasonic nebulizer in Study 2. T...
متن کاملX-ray analysis of disodium cromoglycate.
Disodium cromoglycate (I; DSCG) was introduced in 1968 for the treatment of bronchial asthma. Evidence concerning its principal effects and possible mode of action has been described at some length in the recent literature (Cox, 1971 ; Cox & Altoanyan, 1970). Crystals of the compound exhibit a remarkable reversible water absorption (Cox, Woodard & McCrone, 1971), the number of water molecules p...
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ژورنال
عنوان ژورنال: BMJ
سال: 1970
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.4.5731.337